Serie A official line-ups: Roma vs. Fiorentina
Roma hope Donyell Malen and Matias Soulé can get them within a point of Juventus and fourth place, as Fiorentina rely on Manor Solomon.
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It kicks off at the Stadio Olimpico in Rome at 19.45 UK time (20.45 CEST).
You can follow all the build-up and action as it happens from this game and Cremonese vs. Lazio on the Liveblog.
This could be a big crossroads in the campaign...