Scientists from the V.A. Engelhardt Institute of Molecular Biology of the Russian Academy of Sciences and colleagues conducted a genetic analysis of paragangliomas of the head and neck to identify mutations specific to them.
The authors examined 152 tumor samples from 140 patients collected together with collaborators from the A.V. Vishnevsky National Medical Research Center for Surgery of the Ministry of Health. The biologists extracted DNA from the tumor cells and decoded its sequence.