The multiverse has been good to Magic: The Gathering. Of its recent crossover sets the big winner was The Lord of the Rings, which earned over $200 million in under six months. As Polygon pointed out at the time, that's about twice as much as other popular Magic sets make.
Fallout has apparently been a solid earner as well, although it's not a full set like The Lord of the Rings was. Where the Middle-earth cards were designed to be playable in a variety of formats, and even made it to Magic...