New weight-loss drug wipes out chronic knee pain in some patients, researchers say

An experimental weight-loss drug significantly reduced chronic knee pain and improved mobility in people with obesity and knee osteoarthritis, according to two clinical trials led by researchers at Northwestern University.

The trials, which were funded by Eli Lilly and published in The New England Journal of Medicine, evaluated retatrutide, a once-weekly injectable medication developed by Eli Lilly and Co.

Retatrutide, which is not yet FDA-approved, mimics three hormones involved in appetite and metabolism ...