Alzheimer’s drugs slammed as ‘ineffective’ in major review, but critics push back

A major Cochrane review recently cast doubt on the safety and effectiveness of amyloid-targeting Alzheimer’s drugs, although some experts and drugmakers have disputed the researchers' conclusions.

These types of monoclonal antibodies are designed to reduce or remove amyloid-beta, a naturally occurring protein that can accumulate into sticky plaques in the brains of people with Alzheimer’s disease.

In the review, researchers analyzed results from 17 clinical trials involving 20,342...