Cannabis may backfire for mental health disorders, major study finds

A large body of research found there is little strong evidence that medicinal cannabinoids help with mental disorders and substance-use disorders.

Researchers at the University of Sydney, Australia, reviewed 54 randomized controlled trials, from 1980 to 2025, where cannabinoids (the active substances found in cannabis) were used as the primary treatment.

Most of the 2,477 participants were male (69%) and averaged 33 years old. The paper was published in The Lancet Psychiatry.

STUDY CHALLENGES NEGATIVE CANNABIS STEREOTYPES...