Sinner and Pegula advance to third round at Miami Open
The 24-year-old Italian and reigning Wimbledon champion dispatched 76th-ranked Damir Dzumhur of Bosnia and Herzegovina 6-3, 6-3 on the Florida hardcourts.
"First round matches are never easy, so I'm very happy and let's see what's coming," Sinner said.
He will next face either France's 31st-ranked Corentin Moutet or Czech Tomas Machac.
Four-time Grand Slam winner Sinner, who won the 2024 Miami crown, captured his 25th career ATP title by beating Daniil Medvedev in the Indian Wells final earlier this month.