Top diplomat on Middle Eastern regime change as a losing game: ‘U.S. history in that area of the world is not good with this’

After the largest buildup of U.S. warships and aircraft in the Middle East in decades, American and Israeli military forces launched a massive assault on Iran on Feb. 28, 2026.

President Donald Trump has called the attacks “major combat operations” and has urged regime change in Tehran. Iranian media reported Supreme Leader Ayatollah Ali Khamenei was killed in the strikes.

To better understand what this means for the U.S. and Iran, Alfonso Serrano, a U.S. politics editor at The Conversation...