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Eli Lilly is set to release a once-daily pill to rival Ozempic this year. People are losing 15 to 20 pounds on it, but there's a catch.

People with diabetes lost an average of nearly 20 pounds of body weight during a clinical trial of orforglipron, which is a new small molecule GLP-1 drug.

colnihko/Getty Images

  • Eli Lilly's new GLP-1 pill surged ahead of competitor Novo Nordisk's in a head-to-head trial.
  • Patients on Lilly's pill had better blood sugar levels, lost more weight, and improved heart health.
  • The pill, which analysts say might cost $300 a month, could be available as soon as mid-2026.

Better injections and better pills.

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