How 'Family Guy' Writers Keep Things Fresh After 450 Episodes (Exclusive)

Family Guy is one of the longest-running shows on TV. It first premiered in 1999, only to then get canceled in 2002. But in 2005, Peter Griffin and his dysfunctional family came back with a vengeance, and they’ve been a mainstay of Fox’s Sunday night lineup ever since. 

Season 24 of Family Guy premieres on Feb. 15 with the show’s 450th episode. In the premiere, titled The Edible Arrangement, Stewie and Lois finally are able to hash out their differences — thanks to a wild trip on Brian’s weed gummies.