Anisimova silences Chinese fans to set up Pegula showdown in Melbourne
The fourth seed, who contested two Grand Slam finals last year, kept her cool as temperatures soared to down Wang 7-6 (7/4), 6-4 on John Cain Arena.
She will play Pegula for a place in her first Melbourne Park semi-final after the 31-year-old disposed of defending champion Madison Keys in straight sets.
Anisimova and Pegula have met three times before, with the sixth seed winning them all.
"I'm feeling great. I mean, what a battle out there today. Tough conditions again, against a really good opponent.