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Oprah reveals struggle with 'shame' of weight-loss drugs and what happened when she quit

Longtime talk show host Oprah Winfrey is opening up about her recent weight-loss success after sticking to a GLP-1 (glucagon-like peptide-1).

Winfrey, 71, began taking a GLP-1 medication in 2023, but attempted to quit after six months to see if she could lose weight without it, according to a recent interview with People Magazine. 

Even when sticking to her diet and exercise routines, the media mogul said she gained back 20 pounds after stopping the drug.

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