Oprah joins wave of celebrities who revealed dramatic weight loss in 2025

Celebrities have been striving for health in 2025, with many dropping significant amounts of weight — in many cases with the help of GLP-1 medications like Ozempic.

Below are four A-list stars who shared their weight-loss journeys this year, with or without the help of prescription drugs.

Long-time talk show host Oprah Winfrey was recently featured in an exclusive interview with People Magazine, during which she discussed her weight loss and her new book, "Enough: Your Health, Your...