What to know about the conflict between Israel and Iran, and the U.S. intervention

US Vice President JD Vance, from left, US President Donald Trump, Marco Rubio, US secretary of state, and Pete Hegseth, US secretary of defense, during an address to the nation in the East Room of the White House in Washington, DC, US, on Saturday, June 21, 2025. Trump said the US military struck three sites in Iran on Saturday, marking the first American involvement in direct attacks against Iranian nuclear assets in its conflict with Israel.