NSAIDs vs. acetaminophen: What you need to know before your next headache

Most households have a stash of painkillers tucked away for surprise headaches or stubborn cramps. 

But some may not realize that all painkillers are not created equal, and they don’t all treat the same kind of pain.

Over-the-counter (OTC) pain relievers fall into two main categories, according to MedLine Plus. 

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The first is NSAIDs (non-steroidal anti-inflammatory drugs) like ibuprofen and naproxen.