Christina Applegate and Jamie-Lynn Sigler open up about life with MS on Hoda Kotb’s podcast

In a heartfelt conversation on Hoda Kotb's Making Space podcast, Christina Applegate and Jamie-Lynn Sigler opened up about their personal battles with multiple sclerosis. While Sigler has come to a place of acceptance over two decades, Applegate is still adjusting. The two actresses shared raw emotions, physical challenges, and how MS has shaped their lives differently.